Shambhunath Choudhary

Company: Pfizer

Job title: Associate Research Fellow and Pathology Therapeutic Area Lead

Bio:

Shambhu is a board-certified pathologist and toxicologist with expertise in various fields including nephrotoxicity, hepatotoxicity, dermal toxicity, carcinogenesis studies, vaccine & oncology research, and developing invitro/animal models. He has authored over 40 papers in peer-reviewed international journals and held leadership roles in molecular biology, toxicology, and pathology committees. He is currently an Associate Research Fellow and Pathology Therapeutic Area Lead at Pfizer, having contributed significantly to regulatory documents and nonclinical safety strategies. His educational background includes an MBA, a Ph.D. in Cancer Therapeutics, and a DVM (B.V.Sc. & A.H). He has also completed residences and externships in anatomic pathology and toxicology.

Seminars:

Bridging the Translational Gap in Extrapolating LNP Safety & Immunogenicity in Preclinical Models 11:25 am

Exploring how rodents, non-human primates, and humans differ in complement activation, cytokine responses, and anti-PEG antibody formation to determine immunogenicity Discussing the limitations of rodent and monkey data in forecasting human immunogenicity and toxicity, with examples from mRNA vaccines and therapeutic LNP studies Exploring strategies for dose scaling, biomarker selection, and aligning immune endpoints across…Read more

day: Conference Agenda

Q&A Session 11:50 am

Join our speakers for an interactive Q&A session, where they’ll come together to answer your questions, share further insights, and expand on key themes from their presentations.Read more

day: Conference Agenda