Aparajita Dutta

Company: Orna Therapeutics

Job title: Head of Toxicology

Bio:

Aparajita Dhutta, Ph.D., serves as the Head of Toxicology at Orna Therapeutics, a pioneering biotech company focused on developing fully engineered circular RNA (oRNA) therapeutics. Based in Cambridge, Orna is at the forefront of RNA medicine offering a new class of synthetic circular RNAs designed to overcome the limitations of linear mRNA through improved stability, manufacturability, and protein expression.

Seminars:

Impact of PEGylation on Repeat Dosing: Balancing Immune Responses & Therapeutic Efficacy in LNP Delivery 1:10 pm

Outlining how Orna Therapeutic’s LNP therapeutic programs focusing on linking safety assessment and immune response evaluation Exploring immunogenicity assessment strategies including anti-particle and anti-transgene assays, plus cytokine/chemokine biomarker analysis Advancing toxicology considerations for next-generation LNPs and how integrated safety–immunogenicity data informs safer design decisions.Read more

day: Conference Agenda

Q&A Session 2:15 pm

Join our speakers for an interactive Q&A session, where they’ll come together to answer your questions, share further insights, and expand on key themes from their presentations.Read more

day: Conference Agenda