Striking the Balance Between Wanted & Unwanted Immunogenicity

Time: 1:00 pm
day: Pre-Conference Day Track A PM


Immunogenicity plays a crucial role in various fields such as vaccine development, therapeutic protein production, and gene therapy. This session will equip you with the skills needed to strike a balance between wanted and unwanted immunogenicity and emphasises its position as a critical challenge that requires careful consideration and strategic approaches.

In this session, we will explore:

  • Delineating the specific immune reactions necessary for efficacy from those that may lead to adverse events or reduced treatment effectiveness
  • Developing and utilizing agents that can modulate immune responses, to strike a balance between activation and suppression of the immune system
  • Incorporating adjuvants to enhance the desired immune response, improve vaccine efficacy, and potentially reduce the risk of unwanted immunogenicity
  • Exploring the use of immunomodulatory drugs or biologics to regulate the immune system and fine-tune immune responses
  • Leveraging advancements in genomics, biomarkers, and patient profiling to tailor immunotherapies