Pinpointing & Understanding the Contributions of LNP Components to Toxicity & Their Combined Impact
Time: 9:00 am
day: Pre-Conference Workshop Day
Details:
- Distinguishing the mechanism of toxicity of each individual nanoparticle component to determine the effect and degree each molecule contributes, as well as their combined impact
- Harnessing learnings to influence into novel LNP design with enhanced safety features
- Determining the levels of toxicity elicited by various lipid types within a nanoparticle to influence formulation ratios
- Which chemotypes and molecules should we avoid incorporating into nanoparticles to improve safety profiles? What molecules can we utilize as an alternative?
