Immunological Assessment in in Vitro Models for the Development of Safer LNPs

Time: 1:50 pm
day: Conference Agenda

Details:

• Exploring the safety implications of introducing targeting ligands into LNP systems, including antibodies and peptides as a fifth component beyond the traditional lipid architecture
• Discussing innate immune activation, complement responses, and cytokine profiles from ligand-functionalized LNPs
• Assessing potential off-target effects and unintended biodistribution caused by ligand incorporation to minimize systemic toxicity

Speakers:

Soojin Kim A scientist with over 10 years of specialized iPSC-based neurodegenerative disease research with a primary focus on organelle pathobiology. Skilled in cell and molecular neuroscience Read more