Designing Safer LNPs With Machine Learning: Reducing Immunogenicity & Toxicity Through Predictive Modeling
Time: 10:55 am
day: Conference Agenda
Details:
- Discussing how machine learning models are being trained to predict innate immune activation, cytokine profiles, and complement responses based on LNP composition to optimize lipid and ligand selection early in the design process
- Using algorithm-driven screening to identify novel lipid structures with minimal immune stimulation and improved biocompatibility
- Applying machine learning to triage formulations prior to testing, enabling earlier identification of low-risk candidates and safer design iterations
Speakers:
